Hantavirus Infection in SCID Mice.

Hantavirus infection.

H antavirus has attracted more and more attention as an emerging pathogenic virus in the past decades. It causes two distinct human diseases: Hemorrhagic fever with renal syndrome (HFRS) and human pulmonary syndrome (HPS). Reports on clinical entities possibly caused by hantaviruses in China and England backdate into the first millennium and the Middle Age, respectively (1,2). However, it laste...

Antigenic composition of Borrelia burgdorferi during infection of SCID mice.

The general concept that during infection of mice the Borrelia burgdorferi surface protein composition differs profoundly from that of tick-borne or in vitro-cultivated spirochetes is well established. Specific knowledge concerning the differences is limited because the small numbers of spirochetes present in tissue have not been amenable to direct compositional analysis. In this report we desc...

Pathogenesis of hantavirus infection

Hantavirus Infection in Istanbul, Turkey

To the Editor: More than 20 serotypes of hantavirus have been identifi ed, and 11 infect humans. Puumala virus (PUUV), Dobrava virus (DOBV), and Seoul virus cause different forms of hemorrhagic renal syndrome (1,2). DOBV is endemic to Turkey and countries in the Balkan region. Approximately 10,000–12,000 cases of infection with PUUV and DOBV occur in European Russia each year (3). Initial case ...

Hantavirus infection in children in Argentina.

Clinical hantavirus infection was diagnosed in five Argentine children ages 5 to 11 years by immunoglobulin M (IgM)- capture enzyme-linked immunosorbent assay using Sin Nombre virus (SNV) antigens. Death in three of the children was associated with absence of detectable IgG to SNV antigens. An additional two cases in healthy children were studied: one, a breast-fed 15-month-old whose mother die...